Name: Chicken Pot Pie Casserole Recipe
Prep time: 15 min
Cook time: 30 min
Total time: 45 min
Yield: 4
Cuisine: American
Ingredients: 2 cups chicken, shredded; 1 cup mixed vegetables, frozen (peas, carrots, corn); 1 can (10.5 oz / 298 g) cream of chicken soup; 1 cup milk (240 ml); 1/2 cup cheddar cheese, shredded; 1/2 tsp garlic powder; 1/2 tsp onion powder; salt, to taste; pepper, to taste; 1 can refrigerated biscuit dough

Comfort meets creativity in this delightful chicken pot pie casserole that’ll make your taste buds dance with joy.

Layers of creamy filling nestle between flaky, golden pastry, promising a meal that feels like a warm hug.

Every forkful brings together tender chicken, vibrant vegetables, and a rich, velvety sauce.

Grandma’s classic recipe gets a modern twist with easy-to-follow steps that simplify your cooking adventure.

Home cooks of all skill levels can master this crowd-pleasing dish without breaking a sweat.

Memories of cozy family dinners will flood back as you savor each delectable bite.

You won’t be able to resist sharing this irresistible casserole with everyone around your table.

Chicken Pot Pie Casserole – Classic and Comforting

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No-Bake Halloween Delight: Skip complicated baking processes and enjoy a no-oven recipe that delivers delicious results with minimal kitchen equipment and skills.

Ingredient Rundown for Pot Pie Casserole

For the Protein:

Shredded Chicken: A tender and flavorful base that provides the main protein for this comforting casserole.

For the Vegetables:

Frozen Vegetables: A convenient mix that adds color, nutrition, and texture to the dish.

For the Sauce and Cheese:

Cream of Chicken Soup: Creates a creamy and rich base for the casserole.
Milk: Helps to thin and blend the sauce for a smooth consistency.
Cheddar Cheese: Adds a sharp, tangy flavor and creates a delicious cheesy topping.

For the Seasonings:

Garlic Powder, Onion Powder: Provide depth and enhanced savory flavor to the dish.
Salt, Pepper: Essential for bringing out the overall taste of the ingredients.

For the Topping:

Biscuit Dough: Serves as a golden, fluffy crust that completes the casserole.

Pot Pie Casserole: Directions You’ll Love

Step 1: Warm Up the Oven

Set your oven to a cozy 375F (190C) to create the perfect baking environment for this delightful casserole.

Step 2: Create the Creamy Chicken Blend

In a spacious mixing bowl, combine your ingredients:

Shredded chicken
Frozen vegetable medley
Cream of chicken soup
Milk
Shredded cheddar cheese
Garlic powder
Onion powder

Stir everything together until perfectly blended, creating a rich and creamy mixture.

Step 3: Season with Flavor

Sprinkle in salt and pepper to enhance the taste, adjusting to your personal preference.

Step 4: Prepare the Baking Dish

Transfer the luscious chicken mixture into a greased 9×13-inch baking dish, spreading it evenly across the surface.

Step 5: Top with Biscuit Goodness

Gently separate the biscuit dough and arrange the pieces evenly across the top of the chicken mixture, creating a beautiful golden crust.

Step 6: Bake to Perfection

Slide the dish into the preheated oven and bake for 25-30 minutes.

Watch for the biscuits to turn a gorgeous golden brown and become completely cooked through.

Step 7: Rest and Serve

Allow the casserole to cool for a few minutes, letting the flavors settle and making it easier to serve.

Dig in and enjoy your comforting creation!

Tips for Great Chicken Pot Pie Casserole

Swap frozen vegetables with fresh seasonal produce for enhanced flavor and nutrition.
Use rotisserie chicken for a quicker preparation and richer taste.
Experiment with different cheese varieties like pepper jack or mozzarella for unique flavor profiles.
Add a sprinkle of dried herbs like thyme or rosemary to elevate the dish's complexity.
Reduce sodium by using low-sodium cream of chicken soup and monitoring salt quantities.

Unique Takes on Chicken Pot Pie Casserole

Southwestern Spice Splash: Add diced green chiles, jalapeños, and replace cheddar with pepper jack cheese for a zesty kick.
Mediterranean Herb Haven: Mix in chopped spinach, crumbled feta, and sprinkle oregano and basil for a Mediterranean-inspired version.
Creamy Mushroom Marvel: Incorporate sautéed mushrooms, swap cream of chicken soup with cream of mushroom, and add thyme for an earthy flavor profile.
Bacon Lover's Dream: Crumble crispy bacon on top before baking and fold some cooked bacon bits into the chicken mixture for extra richness.

Serve this hearty casserole alongside a crisp green salad with light vinaigrette to balance the rich, creamy texture. The fresh greens will cut through the dish's warmth, creating a perfectly balanced meal.
Top each serving with fresh chopped parsley or chives for a burst of color and subtle herbal freshness. The green garnish adds a delightful visual appeal and introduces a light, bright note to the comforting casserole.
Pack individual portions in meal prep containers for easy grab-and-go lunches during the week. This dish reheats beautifully and maintains its delicious flavor, making it an excellent option for busy professionals and students seeking a satisfying meal.

Chicken Pot Pie Casserole: Storing Made Simple

Store leftover chicken pot pie casserole in an airtight container in the refrigerator for up to 3-4 days. Keep the container sealed tightly to maintain freshness and prevent odors from spreading.
Wrap the cooled casserole tightly in plastic wrap, then cover with aluminum foil. Freeze for up to 2-3 months. Place a label with the date to track storage time.
Warm individual servings in the microwave for 1-2 minutes, stirring halfway through to ensure even heating. Add a splash of milk to restore moisture if the casserole seems dry.

FAQs

Can I use rotisserie chicken for this recipe?

Yes, rotisserie chicken works great and saves time. Just shred the meat and follow the recipe as directed.

Is this dish freezer-friendly?

Absolutely! You can prepare the casserole, cover tightly with foil, and freeze for up to 3 months. Thaw overnight in the refrigerator before baking.

What if I don't have cream of chicken soup?

You can substitute with cream of mushroom soup or make a homemade white sauce using butter, flour, and chicken broth.

Can I make this recipe gluten-free?

Use gluten-free biscuit dough and gluten-free cream of chicken soup to adapt the recipe for gluten-sensitive diets.

Jack Monroe

Founder & Recipe Innovator

Expertise

Pacific Northwest cuisine, Single-serving recipe development, Sustainable sourcing and cooking, Modern comfort food

Education

Brightwater
Associate of Applied Science in Culinary Arts
Focus: Sustainable cooking, seasonal ingredients, and food systems education

Jack grew up with a fishing rod in one hand and a cast-iron skillet in the other. After graduating from Brightwater: A Center for the Study of Food, he set out to prove that cooking for one could still taste like a feast.
Jack believes that food should feel real: fresh, fearless, and a little wild, just like the rivers he grew up around. For Jack, every single dish is a small adventure, and the best ones are the ones you can cook with heart, not hassle.

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Ingredient Rundown for Pot Pie Casserole