Mac and Cheese Meatloaf Casserole Recipe

Creamy Mac and Cheese Meatloaf Casserole Recipe for Dinner Joy

Comfort food takes an unexpected turn with this mac and cheese meatloaf casserole that combines two classic favorites into one incredible dish.

Creamy pasta layers intermingle with savory ground beef, creating a hearty meal that feels like a warm hug.

Cheesy goodness melts perfectly between tender meat and soft noodles, promising a crowd-pleasing experience.

Families will adore this simple yet satisfying recipe that brings together familiar flavors in a surprising way.

Kitchen magic happens when traditional ingredients blend seamlessly, offering a delightful twist on dinner staples.

Weeknight meals just got a serious upgrade with this crowd-stopping combination that guarantees clean plates and happy smiles.

You won’t be able to resist diving into this irresistible culinary creation that transforms ordinary ingredients into something extraordinary.

Ingredient List for Mac and Cheese Meatloaf Casserole

For the Meat Layer:
  • Ground Beef: A lean protein that provides the hearty base for the meatloaf.
  • Breadcrumbs: Helps bind the meat mixture and adds a light texture.
  • Egg: Serves as a natural binder to hold the meatloaf together.
  • Onion: Adds a subtle sweetness and depth of flavor to the meat mixture.
  • Salt and Pepper: Enhances the overall seasoning of the meatloaf.
For the Mac and Cheese Layer:
  • Macaroni: The classic pasta that creates a creamy base for the cheese sauce.
  • Cheddar Cheese: Provides a sharp and rich flavor to the mac and cheese layer.
  • Milk: Helps create a smooth and creamy texture for the cheese sauce.
For the Topping:
  • Ketchup: Adds a tangy and slightly sweet finish to the casserole.

Preparing Mac and Cheese Meatloaf Casserole

Step 1: Warm Up The Cooking Space

Crank the oven dial to a toasty 350 degrees Fahrenheit (175 Celsius) so it’s ready for our delicious creation.

Step 2: Create The Meaty Base

Grab a mixing bowl and toss in these yummy ingredients:
  • Ground beef
  • Breadcrumbs
  • Egg
  • Diced onion

Massage these together with a sprinkle of salt and pepper until everything hugs perfectly.

Step 3: Build The Meaty Foundation

Press the meat mixture into your baking dish, creating a solid base layer that looks like a hearty meatloaf blanket.

Step 4: Whip Up Cheesy Goodness

In another bowl, combine:
  • Cooked macaroni
  • Shredded cheddar cheese
  • Milk

Stir until the pasta gets totally cozy with the cheese.

Step 5: Layer The Comfort

Spread the mac and cheese mixture smoothly over the meat layer, making sure every inch gets covered.

Step 6: Add A Tangy Splash

Drizzle ketchup across the top like you’re creating a delicious artwork.

Step 7: Bake To Perfection

Pop the dish into the preheated oven and let it cook for 45 minutes. You’ll know it’s done when the meatloaf is fully cooked and the cheese is bubbling with excitement.

Step 8: Rest And Serve

Let the casserole cool down for a few minutes, then slice and serve this ultimate comfort food.

Tricks for Great Mac and Cheese Meatloaf Casserole

  • Enhance flavor by using a mix of ground meats like beef and pork for richer taste.
  • Check internal temperature of meatloaf reaches 160°F (71°C) for food safety.
  • Add extra shredded cheese on top during the last 10 minutes of baking for a crispy golden crust.
  • Replace breadcrumbs with gluten-free alternatives like crushed cornflakes for a gluten-free version.
  • Optional: Sprinkle chopped fresh parsley or green onions before serving to add color and freshness.

Mac and Cheese Meatloaf Casserole – Fun Combos

  • Spicy Southwest Fusion: Add diced jalapeños, chili powder, and swap cheddar for pepper jack cheese for a zesty kick.
  • BBQ Ranch Remix: Replace ketchup with tangy BBQ sauce and sprinkle ranch seasoning into the meat mixture for a bold flavor profile.
  • Italian-Style Classic: Mix in grated parmesan, chopped basil, and marinara sauce instead of ketchup to create a Mediterranean-inspired version.
  • Bacon Cheddar Crunch: Sprinkle crispy bacon bits between mac and cheese layers and top with extra crispy bacon crumbles for added texture and smoky flavor.

Serving Mac and Cheese Meatloaf Casserole

  • Hearty Family Dinner Delight: Serve this mac and cheese meatloaf casserole with a crisp green salad to balance the rich, comforting flavors. The fresh greens will add a light, refreshing contrast to the dense, cheesy main dish.
  • Potluck Party Pleaser: Bring this crowd-pleasing casserole to gatherings and watch it disappear quickly. Cut into neat squares for easy serving and garnish with chopped parsley for a pop of color and fresh herb flavor.
  • Weekend Comfort Meal: Pair this dish with roasted seasonal vegetables like Brussels sprouts or glazed carrots. The caramelized vegetable sides will complement the savory meatloaf and creamy mac and cheese, creating a well-rounded meal that feels like a warm hug.

Mac and Cheese Meatloaf Casserole Storage Advice

  • Store leftovers in an airtight container for up to 3-4 days. Cool the casserole completely before sealing to prevent moisture buildup.
  • Wrap tightly in freezer-safe plastic wrap or aluminum foil. Freeze for up to 2-3 months. Thaw overnight in the refrigerator before reheating.
  • Warm individual portions in the microwave for 1-2 minutes. For best texture, use an oven at 350F (175C) for 10-15 minutes, covering with foil to prevent drying out.
  • Divide into single-serving containers for easy grab-and-go lunches or quick weeknight meals. Label with the date to track freshness.

FAQs

  • Can I use different types of ground meat?

Yes, you can substitute ground beef with ground turkey, chicken, or pork for a different flavor profile while maintaining the same cooking method.

  • Is this recipe kid-friendly?

Absolutely! The combination of meatloaf and mac and cheese makes this dish a guaranteed hit with children, offering both protein and comfort food elements.

  • How can I make this recipe healthier?

Consider using lean ground meat, whole wheat breadcrumbs, low-fat cheese, and adding some finely chopped vegetables to the meat mixture for extra nutrition.

  • What side dishes work best with this casserole?

Green salads, steamed vegetables, or roasted broccoli complement this hearty dish perfectly, balancing the rich and savory flavors of the meatloaf and mac and cheese.

Mac and Cheese Meatloaf Casserole – Ultimate Combo

  • Craft a Comforting Meal: This chicken noodle casserole transforms simple ingredients into a hearty, soul-warming dish that brings families together around the dinner table.
  • Simplify Weeknight Cooking: Combine all ingredients in one bowl, mix, and bake – no complicated techniques required, making it perfect for busy home cooks seeking a stress-free dinner solution.
  • Customize with Ease: Swap vegetables, use different cheese types, or add extra seasonings to match your family's taste preferences, creating a versatile recipe that adapts to your kitchen creativity.
  • Kid-Friendly Crowd-Pleaser: Packed with tender chicken, soft noodles, and melted cheese, this casserole appeals to picky eaters and satisfies hungry appetites with its classic, beloved flavors.
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Mac and Cheese Meatloaf Casserole Recipe

Mac and Cheese Meatloaf Casserole Recipe


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4.8 from 30 reviews

  • Total Time: 1 hour 10 minutes
  • Yield: 4 1x

Description

Hearty mac and cheese meatloaf casserole brings comfort to dinner tables with nostalgic Southern charm. Home cooks will enjoy this classic fusion of creamy pasta and savory ground beef, creating a satisfying meal that warms hearts.


Ingredients

Scale
  • 1 lb ground beef
  • 2 cups shredded cheddar cheese
  • 2 cups cooked macaroni
  • 1 cup breadcrumbs
  • 1 egg
  • 1/2 cup onion, finely chopped
  • 1/4 cup ketchup
  • 1/4 cup milk
  • Salt and pepper to taste

Instructions

  1. Heat oven to 350F (175C), preparing a baking dish for the layered casserole.
  2. Thoroughly blend ground beef with breadcrumbs, egg, and finely chopped onion, seasoning generously with salt and pepper.
  3. Compact the meat mixture into an even, dense layer covering the bottom of the baking dish.
  4. Mix cooked macaroni with shredded cheddar and milk until well combined and creamy.
  5. Carefully distribute the mac and cheese mixture over the meatloaf foundation, ensuring complete coverage.
  6. Artfully drizzle ketchup across the top surface, creating a tangy glaze.
  7. Slide the casserole into the preheated oven and bake for 45-50 minutes, monitoring until the meat is thoroughly cooked and cheese develops a golden, bubbling crust.
  8. Remove from oven and allow the casserole to rest for 5-7 minutes, helping the layers set and flavors meld before serving.

Notes

  • Opt for lean ground beef to reduce excess fat and create a healthier version of this comfort dish.
  • Mix different cheese varieties like sharp cheddar and monterey jack for a more complex flavor profile.
  • Enhance the meatloaf’s moisture by adding grated zucchini or finely chopped bell peppers to the meat mixture.
  • Replace breadcrumbs with crushed gluten-free crackers or almond flour for those with dietary restrictions.
  • Prep Time: 20 minutes
  • Cook Time: 50 minutes
  • Category: Lunch, Dinner
  • Method: Baking
  • Cuisine: American

Nutrition

  • Serving Size: 4
  • Calories: 630 kcal
  • Sugar: 5 g
  • Sodium: 700 mg
  • Fat: 40 g
  • Saturated Fat: 18 g
  • Unsaturated Fat: 18 g
  • Trans Fat: 1 g
  • Carbohydrates: 30 g
  • Fiber: 2 g
  • Protein: 38 g
  • Cholesterol: 120 mg
Jack Monroe

Jack Monroe

Founder & Recipe Innovator

Expertise

Pacific Northwest cuisine, Single-serving recipe development, Sustainable sourcing and cooking, Modern comfort food​

Education

Brightwater
Associate of Applied Science in Culinary Arts
Focus: Sustainable cooking, seasonal ingredients, and food systems education


Jack grew up with a fishing rod in one hand and a cast-iron skillet in the other. After graduating from Brightwater: A Center for the Study of Food, he set out to prove that cooking for one could still taste like a feast.
Jack believes that food should feel real: fresh, fearless, and a little wild, just like the rivers he grew up around. For Jack, every single dish is a small adventure, and the best ones are the ones you can cook with heart, not hassle.

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